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Other - Cost: £652,109,405.62 Empagliflozin (Jardiance) - Cost: £7,788,101.39 Edoxaban (Lixiana) - Cost: £8,056,980.75 Influenza vaccine (Fluad) - Cost: £13,930,057.90 Beclometasone / Formoterol MDI (Fostair) - Cost: £17,160,087.08 Rivaroxaban (Xarelto) - Cost: £20,491,468.20 Apixaban (Eliquis) - Cost: £33,811,997.20
Formulary Notes (BNF Sub Paragraph)
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Notes for: Cortico'oids & Other Immunosuppressants
Last edited [27/06/2012 09:25:49]
Last edited [04/12/2017 16:24:41]

1. Protocols for the monitoring of cytotoxic drugs prescribed by cancer specialists are available within the Trust.

2. CSM Warning: Cardiomyopathy has been reported in children given tacrolimus after transplantation. Patients using the drug should be monitored carefully by echocardiography for hypertrophic changes; dose reduction or discontinuation should be considered if these occur.

3. Because of differences in bioavailability the brand of oral ciclosporin should be specified by the prescriber.

4. MHRA Drug Safety Update (June 2012) The growing number of oral tacrolimus products available on the market increases the potential for inadvertent switching between products, which has been associated with reports of toxicity and graft rejection. Therefore, to ensure maintenance of therapeutic response when a patient is stabilised on a particular brand, oral tacrolimus products should be prescribed and dispensed by brand name only. If a prescriber considers that switching a patient to a different brand of oral tacrolimus would be of benefit, the change requires careful supervision and therapeutic monitoring by an appropriate specialist

 

Cornwall Joint Formulary Recommended Choices     (...Top)
Displaying 22 Drugs

Key:
First Line Drugs First Line Drugs
Second Line Drugs Second Line Drugs
Specialist Initiated Drugs Specialist Initiated Drugs
Hospital Only Drugs Hospital Only Drugs
Discouraged Discouraged
No comment available No comment available
Antibiotics Antibiotics

NameTariffBNF Sub Paragraph
Tacrolimus
5 mg / 1 mL Concentrate for i/v infusion Pack of 1
- PCT FORMULARY STATUS: Specialist Initiated Drugs Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Tacrolimus'View SPC on 'Tacrolimus'View PIL on 'Tacrolimus'
Ciclosporin (Neoral)
25 mg cap Pack of 30
£18.37PCT FORMULARY STATUS: Specialist Initiated Drugs Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Ciclosporin'View SPC on 'Ciclosporin'View PIL on 'Ciclosporin'
Ciclosporin (Neoral)
50 mg cap Pack of 30
£35.97PCT FORMULARY STATUS: Specialist Initiated Drugs Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Ciclosporin'View SPC on 'Ciclosporin'View PIL on 'Ciclosporin'
Tacrolimus (Adoport)
0.5 mgcaps Pack of 50
£42.92PCT FORMULARY STATUS: Specialist Initiated Drugs [Notes:] RCHT Renal Team prefers Adoport brand of Tacrolimus Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Tacrolimus'View SPC on 'Tacrolimus'View PIL on 'Tacrolimus'
RCHT Renal Team prefers Adoport brand of Tacrolimus
Tacrolimus (Adoport)
1 mg caps Pack of 50
£55.69PCT FORMULARY STATUS: Specialist Initiated Drugs [Notes:] RCHT Renal Team prefers Adoport brand of Tacrolimus Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Tacrolimus'View SPC on 'Tacrolimus'View PIL on 'Tacrolimus'
RCHT Renal Team prefers Adoport brand of Tacrolimus
Tacrolimus
0.5 mg cap Pack of 50
£61.88PCT FORMULARY STATUS: Specialist Initiated Drugs Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Tacrolimus'View SPC on 'Tacrolimus'View PIL on 'Tacrolimus'
Ciclosporin (Neoral)
100 mg cap Pack of 30
£68.28PCT FORMULARY STATUS: Specialist Initiated Drugs Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Ciclosporin'View SPC on 'Ciclosporin'View PIL on 'Ciclosporin'
Tacrolimus
1 mg cap Pack of 50
£80.28PCT FORMULARY STATUS: Specialist Initiated Drugs Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Tacrolimus'View SPC on 'Tacrolimus'View PIL on 'Tacrolimus'
Sirolimus (Rapamune)
1 mg Tab Pack of 30
£86.49PCT FORMULARY STATUS: Specialist Initiated Drugs Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Sirolimus'View SPC on 'Sirolimus'View PIL on 'Sirolimus'
Cyclosporin Solution (Neoral Solution)
100 mg/ml Pack of 50
£102.30PCT FORMULARY STATUS: Specialist Initiated Drugs Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Cyclosporin Solution'View SPC on 'Cyclosporin Solution'View PIL on 'Cyclosporin Solution'
Sirolimus solution (Rapamune)
1 mg / 1ml Pack of 60
£162.41PCT FORMULARY STATUS: Specialist Initiated Drugs Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Sirolimus solution'View SPC on 'Sirolimus solution'View PIL on 'Sirolimus solution'
Sirolimus (Rapamune)
2 mg Tab Pack of 30
£172.98PCT FORMULARY STATUS: Specialist Initiated Drugs Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Sirolimus'View SPC on 'Sirolimus'View PIL on 'Sirolimus'
Tacrolimus (Adoport)
5 mg caps Pack of 50
£205.74PCT FORMULARY STATUS: Specialist Initiated Drugs [Notes:] RCHT Renal Team prefers Adoport brand of Tacrolimus Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Tacrolimus'View SPC on 'Tacrolimus'View PIL on 'Tacrolimus'
RCHT Renal Team prefers Adoport brand of Tacrolimus
Tacrolimus
5 mg cap Pack of 50
£296.58PCT FORMULARY STATUS: Specialist Initiated Drugs Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Tacrolimus'View SPC on 'Tacrolimus'View PIL on 'Tacrolimus'
Basiliximab
10 mg vial - injection, powder for reconstitution Pack of 1
- PCT FORMULARY STATUS: Hospital Only Drugs Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Basiliximab'View SPC on 'Basiliximab'View PIL on 'Basiliximab'
Basiliximab
20 mg vial - injection, powder for reconstitution Pack of 1
- PCT FORMULARY STATUS: Hospital Only Drugs Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Basiliximab'View SPC on 'Basiliximab'View PIL on 'Basiliximab'
Lenalidomide
5 mg capsules Pack of 1
- PCT FORMULARY STATUS: Hospital Only Drugs Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Lenalidomide'View SPC on 'Lenalidomide'View PIL on 'Lenalidomide'
Lenalidomide
10 mg capsules Pack of 1
- PCT FORMULARY STATUS: Hospital Only Drugs Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Lenalidomide'View SPC on 'Lenalidomide'View PIL on 'Lenalidomide'
Lenalidomide
15 mg capsules Pack of 1
- PCT FORMULARY STATUS: Hospital Only Drugs Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Lenalidomide'View SPC on 'Lenalidomide'View PIL on 'Lenalidomide'
Lenalidomide
25 mg capsules Pack of 1
- PCT FORMULARY STATUS: Hospital Only Drugs Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Lenalidomide'View SPC on 'Lenalidomide'View PIL on 'Lenalidomide'
Thalidomide
50 mg capsules Pack of 1
- PCT FORMULARY STATUS: Hospital Only Drugs [Notes:] Original pack prescribing / dispensing only Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Thalidomide'View SPC on 'Thalidomide'View PIL on 'Thalidomide'
Original pack prescribing / dispensing only
Ciclosporin (Sandimmun)
50 mg / ml (1ml amp) Pack of 10
- PCT FORMULARY STATUS: Hospital Only Drugs Cortico'oids & Other ImmunosuppressantsView BNF Article on 'Ciclosporin'View SPC on 'Ciclosporin'View PIL on 'Ciclosporin'

 
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