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Cost
Packs
Items
Other - Cost: £627,284,910.54 Trimbow (Beclometasone / Formoterol / Glycopyrronium MDI) - Cost: £7,640,561.00 Empagliflozin (Jardiance) - Cost: £9,180,638.84 Dapagliflozin (Forxiga) - Cost: £10,106,471.61 Edoxaban (Lixiana) - Cost: £10,215,430.75 FreeStyle Libre 2 Sensor  - Cost: £10,470,110.00 Beclometasone / Formoterol MDI (Fostair) - Cost: £16,498,070.80 Rivaroxaban (Xarelto) - Cost: £20,000,452.50 Apixaban (Eliquis) - Cost: £35,469,046.10
Formulary Notes (BNF Sub Paragraph)
NICE Guidance (1)
Other Links (1)
Important Local Documents (0)
Notes for: Breast Cancer
Last edited [27/06/2012 11:43:36]

All women with invasive breast cancer should be considered for adjuvant therapy, which is determined by an assessment of the risk of recurrence, oestrogen-receptor status of the primary tumour, and menopausal status.

 

Last edited [27/06/2012 11:49:01]

NICE guidance (No. 112) Hormonal therapies for the adjuvant treatment of early oestrogen-receptor-positive breast cancer NICE have also issued clinical guidelines (February 2009) on early and locally advanced breast cancer and on advanced breast cancer.

 

Last edited [27/06/2012 11:50:44]

Endometrial Changes. An increased incidence of endometrial changes, including hyperplasia, polyps and cancer, has been reported in association with tamoxifen. Abnormal vaginal bleeding including menstrual irregularities, vaginal discharge and symptoms such as pelvic pain or pressure in those receiving (or who have previously received) tamoxifen should be promptly investigated. Tamoxifen CSM advice: A dose of 20mg daily substantially increases survival in early breast cancer, no further benefit has been demonstrated with higher doses. Patients should be told of the small risk of endometrial cancer and encouraged to report relevant symptoms early. They can, however, be reassured that the benefits of treatment far outweigh the risks.

 

Cornwall Joint Formulary Recommended Choices     (...Top)
Displaying 7 Drugs

Key:
First Line Drugs First Line Drugs
Second Line Drugs Second Line Drugs
Specialist Initiated Drugs Specialist Initiated Drugs
Hospital Only Drugs Hospital Only Drugs
Discouraged Discouraged
No comment available No comment available
Antibiotics Antibiotics

NameTariffBNF Sub Paragraph
Letrozole
2.5 mg tab Pack of 14
£1.04PCT FORMULARY STATUS: Specialist Initiated Drugs Breast CancerView BNF Article on 'Letrozole'View SPC on 'Letrozole'View PIL on 'Letrozole'
Anastrozole
1 mg tab Pack of 28
£1.05PCT FORMULARY STATUS: Specialist Initiated Drugs Breast CancerView BNF Article on 'Anastrozole'View SPC on 'Anastrozole'View PIL on 'Anastrozole'
Tamoxifen
20 mg tab Pack of 30
£2.99PCT FORMULARY STATUS: Specialist Initiated Drugs Breast CancerView BNF Article on 'Tamoxifen'View SPC on 'Tamoxifen'View PIL on 'Tamoxifen'
Exemestane
25 mg tab Pack of 30
£7.81PCT FORMULARY STATUS: Specialist Initiated Drugs Breast CancerView BNF Article on 'Exemestane'View SPC on 'Exemestane'View PIL on 'Exemestane'
Tamoxifen
10 mg tab Pack of 30
£38.01PCT FORMULARY STATUS: Specialist Initiated Drugs Breast CancerView BNF Article on 'Tamoxifen'View SPC on 'Tamoxifen'View PIL on 'Tamoxifen'
Anastrozole (Arimidex)
1 mg Tab Pack of 28
£68.56PCT FORMULARY STATUS: Specialist Initiated Drugs Breast CancerView BNF Article on 'Anastrozole'View SPC on 'Anastrozole'View PIL on 'Anastrozole'
Tamoxifen
40 mg tab Pack of 30
£94.98PCT FORMULARY STATUS: Specialist Initiated Drugs Breast CancerView BNF Article on 'Tamoxifen'View SPC on 'Tamoxifen'View PIL on 'Tamoxifen'

 
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