Notes for: TheophyllineLast edited [22/08/2013 16:06:35]
1. Please specify the brand when prescribing a modified release preparation of theophylline to ensure that the patient receives the same modified release preparation.
2. Theophylline levels are recommended annually or if the patient has symptoms suggestive of theophylline toxicity.
3. Theophylline interactions: The half-life is increased (giving higher theophylline levels) in heart failure, cirrhosis, viral infections, in the elderly and by drugs such as cimetidine, ciprofloxacin, erythromycin and clarithromycin. The half-life is decreased (giving lower theophylline levels) in smokers, and in chronic alcoholism, and by drugs such as phenytoin, carbamazepine, rifampicin and barbiturates.
4. Slo-phyllin® is included for children as the capsules can be opened and the granules sprinkled on soft food prior to administration.