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Other - Cost: £627,266,699.48 Trimbow (Beclometasone / Formoterol / Glycopyrronium MDI) - Cost: £7,640,561.00 Empagliflozin (Jardiance) - Cost: £9,180,638.84 Dapagliflozin (Forxiga) - Cost: £10,106,471.61 Edoxaban (Lixiana) - Cost: £10,215,430.75 FreeStyle Libre 2 Sensor  - Cost: £10,470,110.00 Beclometasone / Formoterol MDI (Fostair) - Cost: £16,498,070.80 Rivaroxaban (Xarelto) - Cost: £20,000,452.50 Apixaban (Eliquis) - Cost: £35,469,046.10
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Notes for: Drugs For Oral Ulceration & Inflammation
Last edited [13/07/2012 11:17:05]

1. Caution: Miconazole and other anti-fungals enhance the anti-coagulant effect of warfarin

2. Oral thrush is often over-diagnosed in the immuno-competent. Prescribing is only recommended where symptomatic thrush has been identified. Oral thrush tends to be more problematic in cancer patients, other immuno-compromised patients, and those on corticosteroids.

3. Failure to respond to treatment (particularly in the immuno-compromised) may indicate mouth ulceration due to herpes. The appropriate swab is required.

 

Last edited [12/08/2013 16:33:50]

1. Benzydamine is useful in palliating discomfort in a variety of ulcerative conditions. It may cause stinging, often reduced by dilution with an equal volume of water.

2. Orabase® is cheap and effective in providing mechanical protection of oral and perioral lesions.

3. Hydrocortisone oromucosal tablets are useful for some forms of mouth ulcers and may be fairly easily placed near or on the ulcer site.

4. Care should be taken using choline salicylate gel as it may itself cause ulceration (salicylate content). It is available over the counter.

5. Bonjela® in not recommended for use in those aged under 16 years.

 

Cornwall Joint Formulary Recommended Choices     (...Top)
Displaying 8 Drugs

Key:
First Line Drugs First Line Drugs
Second Line Drugs Second Line Drugs
Specialist Initiated Drugs Specialist Initiated Drugs
Hospital Only Drugs Hospital Only Drugs
Discouraged Discouraged
No comment available No comment available
Antibiotics Antibiotics

NameTariffBNF Sub Paragraph
Benzydamine Spray
0.15 % spray (30 ml unit) Pack of 1
£2.60PCT FORMULARY STATUS: First Line Drugs Drugs For Oral Ulceration & InflammationView BNF Article on 'Benzydamine Spray'View SPC on 'Benzydamine Spray'View PIL on 'Benzydamine Spray'
Benzydamine Oral Rinse
0.15 % oral rinse SF Pack of 300
£5.00PCT FORMULARY STATUS: First Line Drugs Drugs For Oral Ulceration & InflammationView BNF Article on 'Benzydamine Oral Rinse'View SPC on 'Benzydamine Oral Rinse'View PIL on 'Benzydamine Oral Rinse'
Hydrocortisone Tablets
2.5 mg buccal tab sugar free Pack of 20
£8.96PCT FORMULARY STATUS: First Line Drugs Drugs For Oral Ulceration & InflammationView BNF Article on 'Hydrocortisone Tablets'View SPC on 'Hydrocortisone Tablets'View PIL on 'Hydrocortisone Tablets'
Choline salicylate 8.7% (Bonjela Dental Gel)
15 g tube sugar free Pack of 15
£3.55PCT FORMULARY STATUS: Second Line Drugs Drugs For Oral Ulceration & InflammationView BNF Article on 'Choline salicylate 8.7%'View SPC on 'Choline salicylate 8.7%'View PIL on 'Choline salicylate 8.7%'
Hydrocortisone (Alkindi)
0.5 mg granules in capsules for opening Pack of 50
£33.75PCT FORMULARY STATUS: Specialist Initiated Drugs [Notes:] Alkindi is accepted for cortisol replacement therapy of infants and young children with adrenal insufficiency where the hydrocortisone 10mg tablets cannot be used, either whole or halved, to administer the required dose. Drugs For Oral Ulceration & InflammationView BNF Article on 'Hydrocortisone'View SPC on 'Hydrocortisone'View PIL on 'Hydrocortisone'
Alkindi is accepted for cortisol replacement therapy of infants and young children with adrenal insufficiency where the hydrocortisone 10mg tablets cannot be used, either whole or halved, to administer the required dose.
Hydrocortisone (Alkindi)
1 mg granules in capsules for opening Pack of 50
£67.50PCT FORMULARY STATUS: Specialist Initiated Drugs [Notes:] Alkindi is accepted for cortisol replacement therapy of infants and young children with adrenal insufficiency where the hydrocortisone 10mg tablets cannot be used, either whole or halved, to administer the required dose. Drugs For Oral Ulceration & InflammationView BNF Article on 'Hydrocortisone'View SPC on 'Hydrocortisone'View PIL on 'Hydrocortisone'
Alkindi is accepted for cortisol replacement therapy of infants and young children with adrenal insufficiency where the hydrocortisone 10mg tablets cannot be used, either whole or halved, to administer the required dose.
Hydrocortisone (Alkindi)
2 mg granules in capsules for opening Pack of 50
£135.00PCT FORMULARY STATUS: Specialist Initiated Drugs [Notes:] Alkindi is accepted for cortisol replacement therapy of infants and young children with adrenal insufficiency where the hydrocortisone 10mg tablets cannot be used, either whole or halved, to administer the required dose. Drugs For Oral Ulceration & InflammationView BNF Article on 'Hydrocortisone'View SPC on 'Hydrocortisone'View PIL on 'Hydrocortisone'
Alkindi is accepted for cortisol replacement therapy of infants and young children with adrenal insufficiency where the hydrocortisone 10mg tablets cannot be used, either whole or halved, to administer the required dose.
Hydrocortisone (Alkindi)
5 mg granules in capsules for opening Pack of 50
£337.50PCT FORMULARY STATUS: Specialist Initiated Drugs [Notes:] Alkindi is accepted for cortisol replacement therapy of infants and young children with adrenal insufficiency where the hydrocortisone 10mg tablets cannot be used, either whole or halved, to administer the required dose. Drugs For Oral Ulceration & InflammationView BNF Article on 'Hydrocortisone'View SPC on 'Hydrocortisone'View PIL on 'Hydrocortisone'
Alkindi is accepted for cortisol replacement therapy of infants and young children with adrenal insufficiency where the hydrocortisone 10mg tablets cannot be used, either whole or halved, to administer the required dose.

 
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